Pretty Poisons in the Yard Series: Lillies.

Lily Intoxication in Cats

Faculty of Veterinary Science and the PostGraduate Foundation in Veterinary Science,

The University of Sydney, New South Wales, 2006

Joanna White and Richard Malik  

By Jody Braddock,
Lilies are becoming especially popular as a gift in the Sydney area, and the flowers that are sold are exceedingly toxic to cats. The key to successful treatment of these cats is early recognition of possible ingestion, and aggressive management of the ensuing renal failure. In fact, lily intoxication should be considered as a diagnostic possibility for any cat, regardless of age, suffering kidney failure of sudden onset. More importantly, prevention is much better than attempted cure, so it is in the interests of cat owners and cat lovers to make the danger of lily ingestion WELL KNOWN in the wider community.lthough lilies are flowers commonly used in floral arrangements, and cats often have access to them, most cat owners and florists, and indeed many veterinarians are unaware of lily intoxication as a potential cause of kidney  (renal) failure in cats.             

Indoor cats and especially kittens, may be drawn to floral arrangements, as they are a novel feature in an otherwise very familiar environment that often lacks other forms of vegetation. In the course of investigating the flowers, the cats may play with and sometimes chew parts of the plant. This could easily go unnoticed by owners, or may occur while the cat is alone at home. Similarly, cats with access to lilies growing outdoors in domestic gardens may not be observed to contact the plant, so careful questioning regarding the presence of the plant or flowers is always warranted when a vet is investigating kidney failure in cats, especially when it develops suddenly.

The toxic substance in lilies that injures the kidneys has not been identified, but ALL parts of the lily are poisonous flowers, stamen, stem, leaves and roots. The toxic dose is unknown, but thought to be reached by ingestion of, or mouthing, very small amounts of material.


Cats seem to be unique amongst domestic pets in their susceptibility to this intoxication, possibly due to differences in their metabolism. For the same sort of reason, cats also can be easily poisoned by human medications such as paracetamol, ibuprofen and aspirin, and these too are lethal for cats in doses that would be safe for


humans. Interestingly, dogs that consume large amounts of the plant develop only mild gastrointestinal


signs, while rats and rabbits show no signs of toxicity at all.



Signs of Lily Poisoning

The first signs of toxicity are vomiting, depression and loss of appetite. The onset is usually within 2 hours, and may subside by 12 hours. Although an affected cat is likely to remain depressed, the patient may appear to improve, briefly (with or without symptomatic treatment) as the gastrointestinal signs abate. It is likely, however, that acute renal failure will develop within 24 to 72 hour at which time the cat will become critically ill. At this time the patient may drink much more than usual, or become extremely dehydrated. Your vet might feel painful, enlarged kidneys on physical examination at this stage. If untreated, cats die in 3 to 7 days.

Diagnosis and


Your vet can diagnose the presence of acute renal failure using blood tests, urine tests, an ultrasound examination and possibly a needle biopsy of the kidneys. Although there is no specific test that can identify lily intoxication as the cause with certainty, there are characteristic laboratory findings that make the diagnosis likely if supported by evidence of lily ingestion (see photograph!!). The treatment for lily intoxication is intensive and expensive, typically involving intravenous fluid therapy and hospitalisation for several days. Currently, this would represent a cost in excess of $1000 to most owners, and even with the most diligent therapy, a success outcome is not assured. One very lucky kitten that was diagnosed very early and treated aggressively by the authors is shown in the accompanying photograph. Most cats are not so lucky!

A very lucky kitten who was successfully treated for kidney failure following lily ingestion. Most affected cats are no so lucky!


Lily toxicity should always be considered in any case of acute renal failure in cats. Ingestion of small amounts of plants or flowers of the Liliaceae family can cause severe, irreversible kidney failure and death in cats within 3 to 7 days of exposure. Cats should therefore never have access to flowers or plants of this family.

In an attempt to drive this point home, the Cat Protection Society is developing a laminated poster which we would like to see displayed prominently in every Sydney florist warning potential customers of this risks such a gift may pose to unsuspecting cats. ❦ Page